ARA-290 10mg

ARA-290 is a synthetic 11-amino acid peptide engineered from the helix-B surface domain of erythropoietin (EPO). It is studied for its interaction with the innate repair receptor (IRR) – a heteromeric complex of the erythropoietin receptor (EPOR) and the beta-common receptor (CD131) – which is distinct from the classical EPOR homodimer responsible for red blood cell production.

For research use only. Not for human or veterinary consumption.

Please note, to maintain the quality and integrity of every product, all orders are fulfilled on a made-to-order basis. Please allow 7–14 days for processing and delivery. You will receive tracking details as soon as your order is dispatched.

Research Use Only.

This compound is supplied strictly for in vitro research purposes. It is not approved by the FDA and is not intended for human consumption, therapeutic, diagnostic, or veterinary use. By purchasing, you confirm you are a qualified researcher aged 18+.

Description

ARA-290 is a synthetic 11-amino acid peptide engineered from the helix-B surface domain of erythropoietin (EPO). It is studied for its interaction with the innate repair receptor (IRR) – a heteromeric complex of the erythropoietin receptor (EPOR) and the beta-common receptor (CD131) – which is distinct from the classical EPOR homodimer responsible for red blood cell production.

Key research areas

  • Receptor binding – selectivity for the IRR over the classical EPO receptor homodimer, characterised in vitro
  • Neuroprotection – helix-B-derived peptides studied for neuroprotective activity in cultured cell models
  • Innate immune signalling – studied in cultured urothelial cell models
  • Peptide stability – pyroglutamate N-terminus studied for resistance to exopeptidase degradation versus linear peptide fragments

Product details

  • Class: Non-erythropoietic EPO-derived peptide (IRR agonist)
  • Vial size: 2 mg
  • Sequence: ZEQLERALNSS
  • Molecular formula: C51H84N16O21
  • Appearance: lyophilised white powder
  • Source: chemical synthesis
  • Storage: stable at room temperature short-term; store below -8°C for extended storage
  • Purity: verified by HPLC and mass spectrometry

For research use only. Not for human or veterinary consumption. Not approved by the FDA for the uses described. This information is provided for educational and scientific reference only and is not medical advice.

Shipping & Storage
Shipping: Ships within 48 hours. Temperature-appropriate packaging. Discreet labeling.
Lyophilized: Stable at −20°C for up to 24 months when kept dry and protected from light.
Reconstituted: Store at 2–8°C. Use within 28 days. Do not freeze after reconstitution.
Diluent: Bacteriostatic water (BW) recommended for multi-dose use. See Protocols.